I bought my 2002 trailblazer used in 2008 and it had about 80k on it when I bought it. it is my everyday vehicle and I drive it pretty hard. I have 137k miles on it now and i'm having my first major issue with it. I was using my 4hi and it started grinding while I was driving and had an awful smell filling the car so I pulled over and put it back into 2wd and both the grinding noise and smell went away. other than this issue my only other problems I've had were:
1 replaced both front tie rods
2 replaced all 6 spark plugs
3 replaced 2 ignition coil packs
4 replaced all 4 rotors & brakes
5 replaced rear outer wheel seals
6 replaced rear outer sway bar links
7 replaced tail light cuz I backed into a metal railing and broke it.
8 right rear door handle broke
9 passenger side window motor runs slow
10 replaced blower resistor pack
11 replaced front and rear shocks
12 air filter
13 serpentine belt
that's all I can think of at the moment. I did all my repairs myself. almost everything is just normal car maintenance.
Just because you're mechanically inclined, doesn't make you a mechanic...get a second opinion!